Informatics Research Seminar: Using Real-World Data for Outcomes Research and Comparative Effectiveness Studies

November 11 @ 4:00 – 5:00 pm


Speaker: Christina Mack, PhD, MSPH
Presented from UNC-CH

Broadcast Link: Seminar



This webinar will focus on the strengths and limitations of using existing data sources to address new research questions, in comparison to developing new, prospective patient registries. Dr. Mack will review factors for deciding whether to use existing data sources or collect new data and issues to consider when selecting a data source, drawing on case studies of hybrid and retrospective observational studies as well as prospective registries to illustrate key points.


Christina Mack is Director of Epidemiology and Health Outcomes at Quintiles, responsible for providing scientific leadership on observational research studies and methods initiatives. She is head of Quintile’s Injury Surveillance & Analytics team and lead epidemiologist for professional sports Leagues such as the US NFL. Dr. Mack focuses much of her work on the use of EHR systems and claims data for research, with therapeutic area experience including oncology, infectious disease, pregnancy issues and injury epidemiology. Her technical expertise is in compartative effectiveness study design, propensity scores, instrumental variables, sports injury surveillance methods, and missing data methods.

Dr. Mack holds PhD and Master’s degrees in Epidemiology from the University of North Carolina at Chapel Hill and a degree in Computer Science Engineering from the University of Notre Dame. She is an adjunct Assistant Professor of Epidemiology at the University of Nort Carolina at Chapel Hill and serves on the Board of the Carolina Health Informatics Program.

Prior to her current role, Dr. Mack held positions with Johnson & Johnson, GlaxoSmithKline, the Clinton Foundation, Outcome Sciences (now Quintiles) and the World Health Organization as both a process engineer and epidemiologist. As program manager of large-scale global observational studies, she has been responsible for all operational aspects of large-scale data collection and global study management. Dr. Mack has published manuscipts in leading journals and is a coauthor of the landmark Agency for Healthcare Research and Quality (AHRQ) publication “Registries for Evaluating Patient Outcomes: A User’s Guide” on the topics of Data Elements for Registries, Registries for Medical Devices and Missing Data. She is a regular speaker at conferences as well as public and academic forums on epidemiologic methods, use of existing data for research and careers in research.