Rachel Richesson, PhD was the invited expert for the Clinical Trials Transformation Initiative Registry Trials Project Expert Meeting in Silver Spring, MD on March 30, 2016. The project focuses on the potential to increase efficiencies and decrease costs throughout the ecosystem by embedding clinical trials within registries. During the expert meeting, participants discussed opportunities to use clinical registries in Clinical Trials.
Clinical Trials Transformation Initiative (CTTI) is a public-private partnership to identify and promote practices that will increase the quality and efficiency of clinical trials. Once a specific aspect of the clinical trials process is targeted for improvement, CTTI establishes a project in order to more thoroughly explore the various elements that create the issue at hand. It is comprised of more than 60 organizations from across the clinical trial enterprise. CTTI was established in 2007 by the US Food and Drug Administration and Duke University. CTTI’s approach includes conducting projects to better understand the range of current practices, assess alternative approaches, understand barriers to change, and propose recommendations for improvement. Each member contributes their ideas for projects, participates in their conduct and analysis, and are committed to disseminating CTTI recommendations and encouraging adoption of system changes that will improve the efficiency of clinical trials. CTTI projects result in a variety of deliverables, or products, which can then be used to promote adoption and implementation of the ensuing recommendations.