Informatics Research Seminar: Paradigm Shift in Environmental and Health Risk Assessments in Nano Era

October 28 @ 4:00 – 5:00 pm

 

Speaker: John Bang, PhD
Presented from NCCU

Broadcast Link: Seminar

 

Abstract:

The amount of data generated in scientific and engineering research communities is getting too big and heterogeneous to be processed in a conventional way. In the field of biomedical research, as an example, there are hundreds of articles published daily with additional unpublished study results available in academic communities. Nanotoxicology is one of those areas often showing a wide range of results in the past mainly due to nanomaterial’s distinctive and unique physiochemical properties sometimes completely different from those in macro scale. Carbon nanotubes and silver nanoparticle are two of the most frequently used nanomaterial for their applications in real life. Due to their unique characteristics and popularity for their real life applications, exposure induced toxicity profiles of both have been extensively investigated by a lot of groups around the globe for a long period of time. A wide range of toxicity profiles was created often with contradicting results from different groups mainly due to the lack of standardized testing procedures on these new types of material that few of us had dealt with. Despite the presence of presumed official toxicity profiles made available in recent years, the validity of the profile reports is constantly challenged by new study results. In nanotoxicity studies, different study groups implement different study designs with some levels of design overlap. With so much of archived data available, it becomes more critical to find a way to utilize the existing data with some overlaps. In this presentation, audience will be introduced to a few traditional exposure and risk assessment techniques and associated biomedical research topic in nanotoxicology perspective. Then potential issues of traditional approaches in those studies will be discussed as a way to search for a solution.

Biosketch:

Dr. John Bang majored in Biochemistry at University of Illinois at Urbana-Champaign and continued his medical education at University of Illinois at Chicago/UICOMP and one additional year of tropical medicine at Belize Medical College. He also holds Ph.D. in Environmental Sciences and Engineering from University of Texas at El Paso focusing on nanomaterial characterization. His research expertise is in exposure and risk assessment of environmental pollutants including engineering nanomaterial as well as photocatalytic nanomaterial synthesis for remediation applications. Throughout his research activities, Dr. Bang is aware of the potential benefit of having solid informatics technique for making a meaningful progress in scientific fields, especially those requiring a multidisciplinary approaches.